Familial hyperlipidemia.
نویسندگان
چکیده
منابع مشابه
Frequent detection of familial hypercholesterolemia mutations in familial combined hyperlipidemia.
amilial combined hyperlipidemia (FCH) is the most comon genetic cause of hyperlipidemia, affecting approxiately 1% of the population. It was first described in the eattle Myocardial Infarction Study in 1973 (1). This ondition is characterized by variable lipid phenotypes increased levels of triglycerides or cholesterol or both lipids) n the proband and in relatives that may vary within an ndivi...
متن کاملPlasma lipoproteins in familial combined hyperlipidemia and monogenic familial hypertriglyceridemia.
Plasma lipoprotein concentration, composition, and size were evaluated in two common familial forms of hypertriglyceridemia and compared with those in normal subjects. The very low density lipoproteins (VLDL) were triglyceride-enriched in familial hypertriglyceridemia (triglyceride/apoprotein B ratio: 25.7 +/- 8.9) as compared to normal (9.6 +/- 12.2, P < 0.001) or familial combined hyperlipide...
متن کاملFamilial hyperlipidemia in stroke in the young.
Serum cholesterol, low density lipoproteins (LDL), very low density lipoproteins (VLDL) and chylomicron levels were studied in 25 young patients (age 40 years or less) of non-embolic ischemic stroke of unknown aetiology. Fifteen patients were males and 10 were females. The prevalence of hyperlipidemia was found to be 60%. Frederickson's type IIb hyperlipoproteinemia was the commonest (32%) abno...
متن کاملPulse wave velocity in familial combined hyperlipidemia.
BACKGROUND In the present cross-sectional study we investigated whether familial combined hyperlipidemia (FCH) is associated with an increased arterial wall stiffness, and whether measures of arterial wall stiffness in FCH family members could contribute to cardiovascular risk stratification. METHODS Ninety-eight subjects with FCH and 230 unaffected relatives filled out a questionnaire about ...
متن کاملImpaired activation of adipocyte lipolysis in familial combined hyperlipidemia.
The pathophysiology of familial combined hyperlipidemia (FCHL) is unknown, but altered lipid turnover in peripheral tissues as well as hepatic overproduction of apolipoprotein B have been suggested as possible causes. In the present study, we explored whether a change in triglyceride breakdown by lipolysis in fat cells is present in FCHL. Lipolysis activation by catecholamines was examined in i...
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ژورنال
عنوان ژورنال: Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
سال: 1993
ISSN: 0300-9173
DOI: 10.3143/geriatrics.30.188